Xilometazolin
Xilometazolin adolah bahan aktif nan ado pado ubek semprot hiduang digunokan untuak maradokan hiduang nan tasumbek [1]
 | |
| Data klinis | |
|---|---|
| Palafalan | /ˌzaɪloʊˌmɛtəˈzoʊliːn/ |
| Namo dagang | Otrivin, Otrivine, others |
| AHFS/Drugs.com | Monograph |
| MedlinePlus | a608026 |
| Lisensi data | |
| Kategori pado kahamilan |
|
| Kacondongan katagantuangan | Moderate |
| Rute masuak ubek | intranasal (spray or drops) |
| Kelas ubek | α1 and α2 adrenergic receptor agonist |
| Kode ATC | |
| Status legal | |
| Status legal |
|
| Farmakokinetik data | |
| Eliminasi wakatu paruah | >10 seconds |
| Ekskresi | Urinary |
| Pangenal | |
2-[(4-tert-butyl-2,6-dimethylphenyl)methyl]-
4,5-dihydro-1H-imidazole | |
| Nomor CAS | |
| PubChem CID | |
| IUPHAR/BPS | |
| DrugBank | |
| ChemSpider | |
| UNII | |
| KEGG | |
| ChEMBL | |
| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.007.629  |
| Data kimia jo fisika | |
| Formula | C16H24N2 |
| Molar mass | 244.382 g·mol−1 |
| 3D model (JSmol) | |
N\1=C(\NCC/1)Cc2c(cc(cc2C)C(C)(C)C)C | |
InChI=1S/C16H24N2/c1-11-8-13(16(3,4)5)9-12(2)14(11)10-15-17-6-7-18-15/h8-9H,6-7,10H2,1-5H3,(H,17,18)  Key:HUCJFAOMUPXHDK-UHFFFAOYSA-N | |
 (what is this?) (verify) | |
Deskripsi
suntiangXilometazolin marupokan ubek dalam bantuak semprot atau tetes di hiduang nan digunokan untuak maradokan paradangan jo hiduang nan tasumbek. Ubek iko tamasuak jinih ubek dekongestan nasal nan bakarajo jo caro mangikek reseptor nan samo takah adrenalin. Bahan nan ado pado ubek ko mangikek reseptor alfa-adregenik untuak mangaktifkan sistem adrenal nan manyababkan vasokontriksi sistemik sahinggo mangurangi panyumbatan pado salaput lendir hiduang.[2]
Namo jo Identifikasi
suntiang
- Namo IUPAC : 2-[(4-tert-butyl-2,6-dimethylphenyl)methyl]-4,5-dihydro-1H-imidazole[3]
- Namo InChl : InChI=1S/C16H24N2/c1-11-8-13(16(3,4)5)9-12(2)14(11)10-15-17-6-7-18-15/h8-9H,6-7,10H2,1-5H3,(H,17,18)[3]
- InChl Key : HUCJFAOMUPXHDK-UHFFFAOYSA-N[3]
- Canonical SMILES : CC1=CC(=CC(=C1CC2=NCCN2)C)C(C)(C)C[3]
- Rumus Molekul : C16H24N2[3]
- Nomor CAS : 526-36-3[3]
- Nomor EC (European Community : 208-390-6[3]
Sinonim
suntiang- Ba 11391[4]
- Ba-11391[4]
- BRN 0180542[4]
- EINECS 208-390-6[4]
- Otriven[4]
- Otrivin[4]
- Otrivine[4]
- Otrix[4]
- UNII-WPY40FTH8K[4]
- Xilometazolina[4]
- Xylometazolina[4]
- Xylometazolinum[4]
- Xylomethazoline[4]
Rujuakan
suntiang- ↑ Ghelani, Rita (2019-11-05). "Otrivine adult nasal spray (xylometazoline)". Netdoctor (dalam bahasa Inggris). Diakses tanggal 2021-07-26.[pranala nonaktif permanen]
- ↑ "Xylometazoline". www.drugbank.ca. Diakses tanggal 2020-02-17.
- ↑ a b c d e f g PubChem. "Xylometazoline". pubchem.ncbi.nlm.nih.gov (dalam bahasa Inggris). Diakses tanggal 2020-02-17.
- ↑ a b c d e f g h i j k l m "Drug Information Portal - Mobile - U.S. National Library of Medicine - Drug Search Results". druginfo.nlm.nih.gov. Diakses tanggal 2020-02-19.