Amoksisilin
Amoksisilin marupakan antibiotik nan digunokan dalam pangubatan babagai infeksi bakteri.[1] Ubek ko marupokan lini partamo untuak pangubatan infeksi talingo tangah. Ubek ko bisa lo digunokan untuak mangubati faringitis streptokokus, pneumonia, infeksi kulik, jo infeksi saluran kemih. Ubek ko diagiah sacara per oral.[1]
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| Data klinis | |
|---|---|
| Namo dagang | Amoxil, Tycil, Trimox, others |
| AHFS/Drugs.com | Monograph |
| MedlinePlus | a685001 |
| Kategori pado kahamilan | |
| Rute masuak ubek | Oral, intravena |
| Kode ATC | |
| Status legal | |
| Status legal | |
| Farmakokinetik data | |
| Bioavailabilitas | 95% (pemberian oral) |
| Metabolisme | kurang dari 30% dibiotransformasikan di hati |
| Eliminasi wakatu paruah | 61,3 menit |
| Ekskresi | ginjal |
| Pangenal | |
(2S,5R,6R)-6-{[(2R)-2-amino-2-(4-hydroxyphenyl)-acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-24-carboxylic acid
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| Nomor CAS | |
| PubChem CID | |
| DrugBank | |
| ChemSpider | |
| UNII | |
| KEGG | |
| ChEBI | |
| ChEMBL | |
| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.043.625  |
| Data kimia jo fisika | |
| Formula | C16H19N3O5S |
| Molar mass | 365.4 g/mol g·mol−1 |
| 3D model (JSmol) | |
O=C(O)[C@@H]2N3C(=O)[C@@H](NC(=O)[C@@H](c1ccc(O)cc1)N)[C@H]3SC2(C)C | |
InChI=1S/C16H19N3O5S/c1-16(2)11(15(23)24)19-13(22)10(14(19)25-16)18-12(21)9(17)7-3-5-8(20)6-4-7/h3-6,9-11,14,20H,17H2,1-2H3,(H,18,21)(H,23,24)/t9-,10-,11+,14-/m1/s1  Key:LSQZJLSUYDQPKJ-NJBDSQKTSA-N | |
| (verify) | |
Efek sampiang nan umum tajadi antaro lain mual jo kamerah-merahan.[1] Amoksisilin juo dapek maningkekan risiko infeksi jamur. Katiko digunokan basamo jo Asam klavulanat bisa mangakibatkan efek sampiang diare.[2] Amoksisilin indak buliah digunokan kapado urang nan alergi jo penisilin. Amoksisilin dapek digunokan pado pasien nan punyo masalah ginjal, hanyo sajo dosisnyo paralu diturunkan. Amoksisilin dapek juo digunokan untuk ibu manganduang jo manyusui.[1]
Panamoan
suntiangAmoksisilin marupokan ciek dari banyak penisilin semisintetis nan ditamukan dek ilmuwan Beecham. Paten amoksisilin alah brakhia, dek karano itu sediaan amoksisilin jo co-amoxiclav dijua jo banyak namo nan lain /atau mamiliki beberapa sinonim di saluruah dunia, contoh:
- Actimoxi[3]
- Alphamox
- Almox
- Amimox
- AMOXIZIF
- Amocla
- AMK
- Amoksiklav
- Amorion
- Amoxibactin (animal use)
- Amoxibos
- Amoxiclav
- Amoxidal
- Amoxil
- Amoxin[4]
- Amoxibiotic[5]
- Amoxicilina
- Amoxidal
- Amoxoral (animal use)
- Apo-Amoxy
- Arsogil[6]
- Augmentin
- Bactox
- Bioxidona[7]
- Cilamox
- Clamoxyl
- Clavamox
- Clonamox
- Curam
- Dedoxil
- Dispermox
- Duomox
- Defender[8]
- E-Mox[9]
- Enhancin
- Ezymox[10]
- Gimalxina
- Geramox
- Hiconcil
- Himox
- Isimoxin[11]
- Klavax
- Klavocin
- Klavox
- Lamoxy
- Largopen
- MOX
- Moxatag
- Moxiclav Duo[12]
- Moxikem
- Moxilen
- Moxypen
- Moxyvit
- Nobactam
- Novamoxin
- Optamox
- Ospamox
- Pamoxicillin
- Panklav
- Pinamox
- Penamox
- Polymox
- Senox[13]
- Sinacilin
- Skymox[14]
- Spektramox
- Starmox[15]
- Trimox
- Tolodina[16]
- Tormoxin
- Tyclav[17]
- Unimox
- Vidamox
- Wedemox
- Wymox
- Yucla
- remox
- Zerrsox
- Zimox
- Zoxicillin[18]
Nama tanpa rujukan nan spesifik dirujuak dari situs drugs.com.[19]
Rujuakan
suntiang- ↑ a b c d "Amoxicillin". The American Society of Health-System Pharmacists. Diakses tanggal 1 August 2015.
- ↑ Gillies, M; Ranakusuma, A; Hoffmann, T; Thorning, S; McGuire, T; Glasziou, P; Del Mar, C (17 November 2014). "Common harms from amoxicillin: a systematic review and meta-analysis of randomized placebo-controlled trials for any indication". CMAJ : Canadian Medical Association [Journal de l'Association medicale canadienne]. 187: E21–31. doi:10.1503/cmaj.140848. PMID 25404399.
- ↑ Catalog.md: Actimoxi Linked 2013-12-09
- ↑ Amoxin Linked 2014-07-23
- ↑ Catalog.md: Amoxibiotic Linked 2013-12-09
- ↑ Aversi (Georgia): Arsogil Archived 2013-12-12 di Wayback Machine. Linked 2013-12-09
- ↑ Catalog.md: Bioxidona Linked 2013-12-09
- ↑ DrugsUpdate India: Defender from Sac Pharma Archived 2016-03-04 di Wayback Machine. Linked 2013-12-09
- ↑ Eipico (Egypt): E-Mox Archived 2009-12-15 di Wayback Machine. Linked 2013-12-09
- ↑ DrugsUpdate India: Ezymox from Sac Pharma Archived 2016-03-03 di Wayback Machine. Linked 2013-12-09
- ↑ Catalog.md: Isimoxin Linked 2013-12-09
- ↑ "Moxiclav Duo 500/125". Diarsipkan dari versi asli tanggal 2016-09-08. Diakses tanggal 2016-08-15.
- ↑ BioPortal: Senox Archived 2016-03-04 di Wayback Machine. Linked 2013-12-09
- ↑ PalMediNet: Skymox Linked 2013-12-09
- ↑ Sarthak Biotech India: Starmox Archived 2016-03-04 di Wayback Machine. Linked 2013-12-09
- ↑ Catalog.md: Tolodina Linked 2013-12-09
- ↑ Beximco Pharma, Bangladesh: Tyclav Archived 2014-08-03 di Wayback Machine. Linked 2013-12-09
- ↑ PakMediNet (Pakistan): Zoxicillin Linked 2013-12-09
- ↑ Drugs.com: Amoxicillin Linked 2013-12-09